Hlyukortin 20 (dexamethasone 2 mg), 50 mL
Sterile solution for injection – For veterinary use
DESCRIPTION: Clear solution for injection.
COMPOSITION: 1 ml of the drug contains the active substance: dexamethasone base (as sodium phosphate) 2.0 mg Excipients: sodium metabisulfite, benzyl alcohol, sodium citrate, edetate disodium, propylene glycol, water for injections.
PHARMACOLOGICAL PROPERTIES: Dexamethasone is a synthetic glucocorticosteroid with strong antiphlogistic, antiallergic and other hormonal and metabolic effects. The anti-inflammatory effect of dexamethasone is 25-30 times higher than that of natural cortisone. Corticosteroids, such as dexamethasone, are important in the normal metabolism of protein, carbohydrates, and fats, and control their metabolism in the inflammatory process. Glucocorticoids prevent the development of inflammation: redness, swelling, pain. They also inhibit capillary dilation and phagocytosis and prevent allergic reactions that develop after exposure to the antigen. Dexamethasone mainly affects gluconeogenesis by displacing glycogen in the protein and calcium metabolism by delaying corticotropin secretion. Glucocorticoids also affect the mobilization, oxidation, synthesis and deposition of fats. It can be used in the treatment of adrenal insufficiency, but the drug does not cure the disease, but only relieves symptoms due to anti-allergic and anti-inflammatory effects. Dexamethasone is prescribed for courses of anaphylactic conditions, injuries and concussions of the spinal cord and brain.
APPLICATIONS: Metabolic processes such as: ketosis in cattle or postpartum toxemia in sheep and sows. Non-infectious inflammatory processes, especially acute musculoskeletal inflammation, such as arthritis, periarthritis, tendovaginitis, bursitis, dislocations, muscle inflammation, bones and tendons. Guests have infectious diseases (eg, mastitis, metritis, pneumonia) in combination with appropriate antibacterial therapy. Allergic conditions such as asthma, allergic skin lesions (eczema, urticaria, etc ..) laminitis in horses and cattle, snake bites. Stress and shock. Anaphylactic shock.
DOSAGE: For intramuscular and intravenous use. Treatment with dexamethasone as with other hormones should be individualized. The following doses are recommended for the treatment of inflammatory and allergic inflammatory processes: Cattle: daily dose 2.5-7.5 ml. (5.0-15.0 mg). If necessary, the dose can be repeated. Calves, goats, sheep and pigs: daily dose 1-2.5 ml (2.0-5.0 mg). If necessary, the dose can be repeated. Dogs: daily dose 0.25-0.5 ml (0.5-1.0 mg). If necessary, the dose can be repeated. Cats: daily dose 0.06-0.25 ml (0.125-0.5 mg). If necessary, the dose can be repeated. For the treatment of bovine ketosis, the dose is 2.5 to 10 ml per animal intramuscularly per day, depending on the severity and duration of the symptoms. In shock and adrenocortical crisis in dogs and cats, a single intravenous injection of 4-6 mg / kg body weight is recommended. In shock conditions in cattle, the recommended dose is 1-4 mg / kg. To induce labor once in a dose of 10 ml after 260 days of pregnancy. Childbirth should begin within 48-72 hours. If labor has not begun, the dose can be repeated. Animals receiving dexamethasone should be monitored continuously. Follow aseptic rules when using.
CONTRAINDICATIONS: Contraindicated in the last trimester of pregnancy, due to the fact that it can cause premature birth and abortion. Do not use in animals suffering from diabetes, chronic nephritis, renal failure, congestive heart failure, osteoporosis, except in emergencies. Do not use for viral infections in the stage of viremia.
PERIOD OF COMPLETE EXTRACTION OF THE PREPARATION FROM ANIMAL ORGANISM: Meat of cows, goats – 7 days meat of pigs – 2 days milk – 1 day. The meat and milk obtained before that time are disposed of or fed to unproductive herbs, depending on the opinion of the veterinarian.
PHARMACEUTICAL FORM: Bottles of dark glass of 50 ml. STORAGE: Store in a dark place at a temperature of + 15 ° C to + 25 ° C Shelf life -3 years. For use in veterinary medicine!