Rimadyl P 100 mg, 20 tablets
Rimadyl R, analgesic for dogs, 20 mg, pack. 20 tab., Zoetis Inc
A drug for the relief of inflammation and pain in acute and chronic diseases of the musculoskeletal system in dogs, for the analgesia of pain and edema.
Composition: Rimadyl R is a non-steroidal anti-inflammatory drug in the form of tablets for oral administration, containing carprofen as an active agent – 20 mg, 50 mg or 100 mg per tablet, and as auxiliary substances, spray-dried pork liver powder, hydrolyzed vegetable protein, corn starch, confectionery sugar, glucose syrup, type A gelatin, magnesium stearate, and lactose monohydrate.
Dosage form: In appearance, Rimadyl R with liver flavor is light brown tablets with an embossed letter “R” on one side of the tablet and a dividing groove on the other side.
Packaging, storage conditions, shelf life: Rimadyl R tablets with liver taste in 20, 30, 50, 60, 100 or 180 tablets are packed in square vials made of white high density polyethylene with a polypropylene cap that cannot be opened by children. Each bottle in Russian is labeled with the name of the medicinal product, the name of the manufacturing organization and its address, the name and content of the active substance, purpose, storage conditions, batch number, date of manufacture and expiration date, with the inscription “For animals”. Store with caution (list B), in a dry, dark place out of the reach of children at temperatures from 0 to 25? C. Shelf life 3 years from the date of production, provided that it is stored in the original packaging. Do not use Rimadil R after the expiration date.
Pharmacological properties: Carprofen, the active ingredient of Rimadyl R, belongs to the group of non-steroidal anti-inflammatory drugs, and has anti-inflammatory, analgesic and antipyretic effects.
Carprofen, like other non-steroidal anti-inflammatory drugs, inhibits cyclooxygenase in the arachidonic acid cycle. In this case, the drug predominantly affects cyclooxygenase-II, which is induced in response to the development of inflammation. As a result, the synthesis of inflammatory prostaglandins, which cause inflammation, swelling and pain, is blocked. In therapeutic doses, carprofen has a much weaker effect on cyclooxygenase-I, and therefore does not affect the synthesis of protective prostaglandins. Thus, carprofen does not interfere with normal physiological processes in tissues, especially in the stomach, intestines, kidneys and platelets. Carprofen is rapidly absorbed from the gastrointestinal tract, reaches a peak plasma concentration in 1-3 hours after administration, with a bioavailability of more than 90%. The elimination half-life in dogs is approximately 8 hours. Carprofen is more than 99% bound to plasma proteins. The drug is metabolized in the liver, excreted mainly in feces (about 80%), and in the urine.
The order of application, indications, dose, possible side effects, contraindications: Rimadil tablets with liver taste are prescribed for inflammatory and painful phenomena occurring in acute and chronic diseases of the musculoskeletal system. Rimadyl tablets are also used for analgesia and as an anti-inflammatory agent to reduce postoperative pain and swelling. Liver-flavored Rimadyl tablets are administered orally during the initial period of treatment in
a daily dose of 4 mg of carprofen per 1 kg of body weight. It is recommended to divide the daily dose into two equal parts. After 7 days of treatment, depending on clinical indications, the daily dose can be reduced to 2 mg / kg body weight.
In case of diseases of the musculoskeletal system, the duration of treatment depends on the condition of the animal and, under the supervision of a veterinarian, can continue throughout the life of the animal. Do not exceed the prescribed dose. As with the use of other non-steroidal anti-inflammatory drugs after the use of Rimadil R in individual animals, in rare cases stomach irritation and vomiting may occur. It is forbidden to apply Rimadyl to puppy bitches.
Do not prescribe other non-steroidal anti-inflammatory drugs or nephrotoxic drugs earlier than 24 hours after the administration of Rimadyl R. Rimadyl R, like other non-steroidal anti-inflammatory drugs, should be prescribed with caution to animals with heart, kidney and liver diseases.
Personal precautions: When working with Rimadil R, you should follow the general rules of personal hygiene and safety measures provided for when working with medicines. As with any other medicines, after work, wash your hands thoroughly with warm water and soap.
It is forbidden to take food and water during work.