DESCRIPTION

Sugar-coated tablets.

COMPOUND

One tablet contains the active ingredient:

ronidazole – 30 mg.

Excipients: polyvinylpyrrolidone, potato starch, calcium stearate, talc, albumin, milk powder, flavoring, lactose.

PHARMACOLOGICAL PROPERTIES

ATCvet QP51 – antiprotozoal veterinary drugs.

Ronidazole (a group of nitroimidazole compounds) acts on the simplest, Trichomonas and anaerobic bacteria. The combination of the reaction products of ronidazole with the DNA of protozoan cells or bacteria leads to its death. The creation of strong compounds significantly enhances the acidic intracellular pH level, which, among other things, confirms the selective action of 5-nitromidazole derivatives against anaerobic bacteria and some protozoa. In addition, the reaction of ronidazole creates products that are intracellular donors of aerobic free radicals, which further damage intracellular molecules other than DNA. This increases cellular destruction and leads to the rapid death of protozoa or bacteria.

After oral administration, ronidazole is almost completely rapidly absorbed from the digestive tract and reaches maximum plasma concentrations after 12-14 hours. Its bioavailability is more than 90%. Ronidazole lasts approximately 11 hours in plasma after oral administration in most animals, blocking its reproduction by inhibiting DNA synthesis. Ronidazole, when administered to animals with a single oral dose, has shown that 30-36% of the dose is excreted in the urine and 16-40% in the feces within 24 hours. Subsequent excretion is slow and incomplete.

The drug in recommended doses does not have a sensitizing, embryotoxic or teratogenic effect.

APPLICATION

Prevention and treatment of pigeons and ornamental birds with trichomoniasis (Trichomonas gallinae), hexamythiasis (Hexamita columbae), Cochlosoma spp. and other protozoal diseases, dogs and cats with diseases of the gastrointestinal tract and other organs and tissues caused by the protozoa Trichomonas spp. Giardia spp.

DOSAGE

Dogs : in the treatment of animals affected by giardiasis (giardiasis) Giardia spp. tablets are administered orally, once a day at a dose of 30–50 mg per 1 kg of animal body weight for a course of 7 days.

Cats : when treating animals affected by giardiasis (giardiasis), tablets are used orally, 1 time per day, at a dose of 30 mg per 1 kg of animal body weight for 7 days.

When treating infections caused by Trichomonas foetus, the drug is administered orally once a day at a dose of 30 mg per 1 kg of animal body weight for a course of 14 days.

Pigeons For the treatment and prevention of trichomoniasis (Trichomonas gallinae), hexamythiasis (Hexamita columbae) and other protozoal diseases in pigeons and ornamental birds.

The recommended prophylactic dose is 1 tablet per pigeon. Course of treatment: 1-3 days.

The recommended therapeutic dose is 1 tablet per pigeon. Course of treatment: 3-5 days.

CONTRAINDICATIONS

Hypersensitivity to the components of the drug.

Do not use in cats, dogs and birds with signs of viral infection, dysfunction of the nervous system, kidneys and liver.

Do not use on pregnant or lactating animals.

WARNING

Use the drug according to the recommendations for use.

Recommended doses should be followed.

Treatment of animals and birds must be combined with disinfection of premises, enclosures, cages where sick animals and birds are kept in order to avoid re-infection.

It is advisable to bathe pets with shampoo to wash away any parasite spores that get on their fur.

Release form

Polymer containers of 50 tablets. Secondary packaging – a cardboard box with a postcard insert.

Storage

Dry, dark, inaccessible to children and animals, at a temperature of 5 to 25 °C.

Best before date

3 years.

For use in veterinary medicine!