Brovermectin gel Horse Wormer contains Ivermectin, 60 ml
Storage
1 ml of the drug contains:
ivermectin – 4 mg
Description
Gel of white color, uniform consistency.
Pharmacological properties
Ivermectin belongs to the chemical group of macrocyclic lactones. The pharmacological action is to block the conductivity of chloride ion channels, which disrupts the transmission of nerve impulses and leads to paralysis and death of parasites. Releases inhibitory neurotransmitter (gamma-aminobutyric acid) from presynaptic nerve endings, binds to postsynaptic receptors and opens chloride channels. This leads to hyperpolarization of neurons, their dysfunction and subsequent paralysis of parasites.
It is better absorbed when taken orally than when administered subcutaneously. It has lipophilic properties and is deposited in adipose tissue, regardless of the method of application. The body of animals eliminates it gradually, which prolongs the antiparasitic effect of the drug for up to 3 weeks.
Absorption of drugs with ivermectin is very high, although it occurs gradually. In animals with a single-chamber stomach, it is about 95%. Up to 90% of the administered dose is excreted during the first 4 days. The maximum concentration in blood plasma is observed on average in 6 hours and makes 21,4-82,3 ng / ml.
Indication
Treatment and prevention of horses for diseases caused by:
- Parascaris horses, Oxyuris horse, Strongylidae tribe, Cyathostomidae tribe, Strongyloides westeri, Habronema spp., Draschia megastoma;
- airway nematodes Dictyocaulus arnfieldi;
- filariasis nematodes Parafilaria multipapillosa, Onchocerca cervicalis;
- larvae of gastrointestinal insects Gasterophilus spp.
Contraindication
Do not prescribe to foals under 4 months of age.
Method of application and dosage
The drug is injected into the root of the tongue with a syringe-tube once.
The dose is 1 ml per 20 kg of animal body weight.
Reservation
After the last application of the drug slaughter of animals for meat is allowed in 34 days. Meat obtained before this date can be used only for the production of meat and bone meal and feeding carnivores.
Storage conditions
In a dry, dark place at a temperature of +1 to +20 ° C.
Expiration date
2 years.
