Kefan 10% (ketoprofen) (Ketofen analog)
Ketoprofen is a substance from the group of carboxylic acids, derivatives of propionic acid. The mechanism of action is to inhibit the synthesis of prostaglandins and thromboxane and is based on disruption of arachidonic acid metabolism. In therapeutic doses, ketoprofen inhibits mainly COX-II and partially COX-I, providing anti-inflammatory, analgesic, antipyretic and antiendotoxic effects.
After a single intramuscular injection, the maximum concentration of ketoprofen in blood plasma is observed after 30 minutes. Ketoprofen is excreted mainly by the kidneys.
Treatment of cattle, pigs, horses in acute or chronic inflammatory processes of the musculoskeletal system (arthritis, osteoarthritis, bursitis, dislocation, edema, tendovaginitis, trauma, infectious lesions of the hooves), respiratory organs, metritis-mastitis-agalactia, various forms of mastitis, pain of various etiologies (surgery, trauma, colic). Used as an antipyretic in diseases accompanied by hyperthermia and depression.