Artrolik Max “ZooHels” 100 tab.

Artrolik Max “ZooHels” 100 tab.

Description
flat cylindrical tablets scored without shell cream color with brown patches with a specific smell. Zoohels ARTROLIK Available in two versions: Zoohels ARTROLIK (for small breeds of dogs and cats, 0.5 g tablets) and Zoohels ARTROLIK Max (for medium and large dog breeds tablets 2 g).

Ingredients
1 g tabletmassy includes:

hlyukozaminu hydrochloride – 250 mg,

hondroyitynu sulfate – 102 mg,

metilsulfonilmetan – 75 mg.

Excipients matter: mikrotselyuloza, polyvinyl yeast, talc, manganese sulfate, calcium stearate, vitamin C.

Pharmacological properties
Zoohels ARTROLIK is a complex of biologically active substances: glucosamine hydrochloride, chondroitin sulfate and methylsulfonylmethane which are easily digestible and accessible to the body shape. Glucosamine and chondroitin sulfate, a natural component of connective tissue, anti-inflammatory, desensitizing and chondroprotective effects on bone and cartilage of the joint system. Additional income chondroitin and glucosamine to animals is particularly necessary during recovery after injury and surgery, severe exercise in business and sporting dogs. In dogs experiencing systemic stress on the joints, especially with age decreases the amount of joint fluid, reducing the elasticity called ; compulsory system and degenerative processes in the cartilage. Glucosamine and chondroitin sulfate reducing the severity and intensity of expression of degenerative changes in the joint, reduce the likelihood of developing diseases of the musculoskeletal system of the animal. Glucosamine increases levels hlyukozaminohlikaniv in the joint, which in turn are the building blocks of cartilage in the recovery. Glucosamine stimulates the synthesis of collagen, has antioxidant effects, inhibits lysosomal enzymes (which destroy cartilage), reduces symptoms of adverse reactions to chemotherapeutic agents protecting animals when used in conjunction preventive measures with non-steroidal anti-inflammatory drugs and steroid. It stimulates the regeneration of cartilage tissue. Glucosamine and chondroitin sulfate are involved in the synthesis of connective tissue, helping to prevent cartilage destruction processes and stimulating the regeneration of tissue. Introduction of exogenous glucosamine increases the production of cartilage matrix and provide non-specific protection against chemical damage cartilage. Glucosamine as sulfuric salt is a precursor hexosamine and sulfate anion required for the synthesis of glycosaminoglycans. Another possible function of glucosamine is to protect the damaged cartilage from metabolic destruction caused by NSAIDs and corticosteroids, and our own moderate anti-inflammatory effect. Chondroitin sulfate whether he absorbed yntaktnoy form or as individual components, serves as an additional substrate for the formation of healthy cartilage matrix. It stimulates the formation hialuronona synthesis of proteoglycans and collagen type II, and hialuronon protects against enzymatic degradation (by inhibiting the activity of hyaluronidase) and the harmful effects of free radicals; supports ; viscosity of synovial fluid and stimulates mechanisms of restoration of cartilage and inhibits the activity of enzymes that break down cartilage (elastase, hyaluronidase). In the treatment of osteoarthritis relieves symptoms of the disease and reduce the need for NSAIDs.

Biodostupnist oral glucosamine – 25% (effect & laquo; first pass & raquo; through the liver). The largest concentrations are found in liver, kidney and the articular cartilage. About 30% of the dose long persist in the bone and the city ; muscle tissue. Excreted primarily in the urine in unchanged form; partially – with the feces. T1 / 2 – 68 hours. Chondroitin sulfate: ingestion plasma concentration increases dramatically within 24 hours. Bioavailability – 12%. About 10 and 20% of the dose absorbed in the form of high and low molecular derivatives, respectively. The volume of distribution – about 0.44 mg / ml. Desulfiruvannya metabolized. Excreted in the urine. T1 / 2 – 310 min.

Metilsulfonilmetan (organic sulfur, MSM) – a source of sulfur, provides the molecular structure of the protein part of many amino acids involved in the synthesis of antioxidants, particularly glutathione. Sulfur is needed for the joint tissue, which is responsible for the stability of the cartilage tissue, capsules and called ; yazok. MSM positive effect for pain in the joints, helps restore joint mobility, and improve the permeability of cell walls, allowing fluids and dissolved substances more easily penetrate cell membranes. This facilitates the removal from the cell substances such as lactic acid and toxins, and entering the cells of nutrients and minerals. MSM prevent an increase in intracellular pressure, relieves pain.

Vitamin C, has anti-inflammatory properties and decongestants, contributes to the activation kollahenoobrazovanyya in bone, cartilage and vascular tissues, inhibits the destruction of joints due to its antioxidant action.

Marhanets – necessary element that acts on the growth and development of the connective tissue. It is necessary for the synthesis of glucosamine. When manganese deficiency slows down the synthesis of cartilage and synovial fluid. It is also proved its antioxidant effect.

Pyvni yeast – a natural source of protein and vitamins, effective therapeutic and prophylactic. In brewer’s yeast are: carbohydrates; fourteen vitamins: All B vitamins (choline, thiamin, pyridoxine, pantothenic acid and folic acid) and vitamin E, PP, H, pro-vitamin D and others; essential fatty acids, enzymes: & beta; -fruktofuranozydazy, glucosidase, peptidases, proteases; large amount of minerals: calcium, magnesium, manganese, zinc, iron, phosphorus, selenium and others.

Zoohels Artrolik the degree of influence on the body of warm-blooded animals refers to low-risk substances and recommended doses does not locally irritating and sensitizing action.

Application
Assign dogs and cats for the prevention and comprehensive treatment of inflammatory and degenerative diseases of the musculoskeletal system (arthritis, arthritis, osteoarthritis, osteoarthritis , osteochondrosis, osteohondropatyya, osteoporosis, joint dysplasia) arising against injuries of different origin, age-related changes, with increased physical exertion. In the recovery period after surgery on the locomotor apparatus animal to accelerate reparative processes.

Dosage
Zoohels Artrolik fed directly from the hand, or crushed form of food. Recommended daily dose divided into 2-3 receptions.

pryznachennya DoZooHels ARTROLIK ZooHels ARTROLIK MAKSI

(Tablets 0.5 g) (2 g tablets)

dogs

For the prevention of:

young, growing

tvarynam 1 table. 10 kg Table 0.5. 20 kg

The intensive

vidnovlennya cartilage and

suhlobiv dogs with

vysokym load Table 2. 10 kg Table 1. 20 kg

If dysplasia

tazostehnovyh joints

Or in inflammation of the joints Table 3. 10 kg Table 1.5. 20 kg

koty

The prevention:

molodnyaka, kittens

in growth period 1 table. 3 kg —

The intensive

reheneratsiyi joints,

The aging cats Table 2. 3 kg —

Zoohels ARTROLIK be used for at least 6-8 weeks, prophylactic use is recommended to repeat at intervals of 3 months. Perhaps the constant use.

Application Zoohels ARTROLIK not preclude the appointment of chemotherapeutic agents protecting animals, vitamin-mineral complexes and supplements.

Side effects
in rare cases, some animals are sensitive to the components of the feed additive may experience allergic reactions. Use of the drug in this case, stop.

Contraindications
The increased sensitivity of animals to the drug, severe liver and kidney.

Product
jars of polymeric materials for 100 tablets (tablets 2 g) and 120 tablets (tablets 0.5 g).

Storage
In a dry, dark place inaccessible to children or animals. Apart from food and feed products in packaging at temperatures from 0 to 25 & deg; S.Shelf life– 2 years