COMPOSITION AND FORM OF ISSUE
Floron 30% is an antibacterial drug containing 300 mg of florfenicol as an active ingredient in 1 ml, as well as auxiliary components water and dimethyl sulfoxide. It is a transparent solution of a thick consistency from light yellow to dark yellow, well soluble in water, with a specific odor. Packaged in 100 ml bottles made of dark glass, which are packed in cardboard boxes.
Florfenicol, which is part of the drug, is a thiamphenicol derivative, in the molecule of which the hydroxyl group is replaced by a fluorine atom. Floron 30% has a broad spectrum of antibacterial action, active against Actinobacillus pleuropneumoniae , Pasteurella multocida , Pasteurella haemolytica , Bordetella bronchiseptica , Haemophilus spp ., Mycoplasma hyopneumoniae , Mycoplasma hyorhinis , Salmonella spp ., Staphylococcus aureus , Streptococcus suis , Fusobacterium necrophorum , Bacteroides melaninogenicus , Moraxella bovis… Effective against bacteria that produce acetyltransferase and are resistant to chloramphenicol. Floron 30% acts bacteriostatically. Florfenicol, binding in the protoplasm of a bacterial cell with the 70S ribosomal subunit, blocks the peptidyl transferase enzyme, which leads to inhibition of protein synthesis at the ribosome level in sensitive microorganisms. When administered intramuscularly, florfenicol is well and quickly absorbed and penetrates into all organs and tissues of the body. The maximum concentration of the antibiotic in the blood is reached in pigs after 2.5 hours. The therapeutic antibacterial concentration remains in the organs and tissues of animals for 48 hours. Florfenicol and its metabolites are excreted from the body mainly in the urine and to a lesser extent in the feces.
Prescribed to pigs for the treatment of diseases of bacterial etiology: pleuropneumonia caused by Actinobacillus pleuropneumoniae and / or Haemophilus parasuis , atrophic rhinitis caused by Pasteurella multocida , Bordetella bronchiseptica , as well as other infectious diseases caused by microorganisms sensitive to florfenicol, as well as.
DOSES AND METHOD OF APPLICATION
Floron 30% is administered to pigs intramuscularly twice with an interval of 48 hours at the rate of 15 mg of florfenicol per 1 kg of animal weight, which corresponds to 1 ml of Floron 30% per 20 kg of animal weight. When the solution is injected in a volume exceeding 10 ml, injections are carried out in several places.
In some cases, when using Floron 30%, pigs may experience redness or edema of the perianal region and soft feces, which quickly disappear after the drug is discontinued.
Individual hypersensitivity to florfenicol. It is prohibited to use Floron 30% for the treatment of sows during pregnancy and lactation, as well as breeding boars. The simultaneous use of Floron 30% with thiamphenicol and chloramphenicol, as well as mixing it in one syringe with other drugs is not allowed.
Slaughter of pigs for meat is allowed 14 days after the last application of Floron 30%. In the event of the forced slaughter of animals before the established deadline, the meat is used to feed carnivores or for the production of meat and bone meal.
C precaution according to the list B. In a dry, protected from light and inaccessible to children and animals at a temperature of 5 to 25 ° C. Shelf life – 2 years, after the first opening of the bottle – no more than 30 days.