Indications

Gastrointestinal and respiratory infections caused by trimethoprim and sulfadiazine sensitive micro-organisms, like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus, and Streptococcus spp. in calves, sheep, goats, poultry, and swine.

Contraindications

Hypersensitivity to trimethoprim and/or sulfonamides. Administration to animals with seriously impaired renal and/or hepatic function or with blood dyscrasias.

Side effects

After long-term treatment and high dosages, crystalluria can occur. When symptoms of crystalluria occur (haematuria, kidney colic), treatment has to be stopped immediately and for example, sodium carbonate (alkalinizes) has to be administered for increasing urine solubility of sulfadiazine. Administration for a prolonged period also increases the risk for blood dyscrasias. Anaemia, leucopenia, and thrombocytopenia.

Dosage

For oral administration: Calves, goats, and sheep: Twice daily 5 ml per 100 kg bodyweight for 4 – 7 days. Poultry and swine: 1 liter per 1500 – 2500 liters of drinking water for 4 – 7 days. Note: for pre-ruminant calves, lambs, and kids only. Shake well before use.

Withdrawal times

– For meat: Calves, sheep, goats, and swine: 8 days. Poultry: 5 days.