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Lidocaine hydrochloride
lidocaine-hcl-50-ml
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Home Analgesic ♦ Sedative ♦ Antispasmodic Lidocaine Hydrochloride 20mg Injection Solution 50 ml
Zylkene 225 mg cap 10 39.90 € 30.20 €
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Antisedan (atipamezole) Solution for Dogs and Cats ● No prescription
Antisedan (atipamezole) Solution for Dogs and Cats 10 ml 104.90 € 84.80 €
Brovafarma, Ukraine

Lidocaine Hydrochloride 20mg Injection Solution 50 ml

27.00 € 22.00 €

Animals

Cats, Cattle, Dogs, Goats, Horses, Pigs, Sheep

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Brovafarma, Ukraine

Form

Solution

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Sedazin, 50 ml (Xylazine)
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1 g of the drug contains sodium thiopental
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31.00 € 24.99 €
1 × Zilkene 75mg 10 cap
28.00 € 21.20 €
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SKU: Lidocaine HCl-50ml-BF Category: Analgesic ♦ Sedative ♦ Antispasmodic Tag: Lidocaine hydrochloride
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Description

Lidocaine Hydrochloride Injection 20mg  – 50 ml (Anesthetic)

Composition

1 ml of the drug contains:

lidocaine hydrochloride – 20 mg

Description

The liquid is colorless, and transparent.

Pharmacological properties

Lidocaine hydrochloride – a derivative of acetanilide, belongs to the group of aminoamide agents for local anesthesia, which deprives a limited area of ​​the body from pain sensitivity. The action consists of stabilizing the neuronal membrane, reducing its permeability to sodium ions, which prevents the conduction of impulses along the nerve fibers. Antagonism with calcium ions is possible. It is rapidly hydrolyzed in a weakly alkaline environment of tissues and after a short latency period, it acts for 60-90 minutes. The anesthetic effect is 2-6 times stronger than procaine but decreases with tissue acidosis. Effective for all types of local anesthesia, has moderate vasodilatory and sedative properties.

When administered intramuscularly, the maximum concentration in the blood is reached in 5-15 minutes, the anesthetic effect begins in 2-5 minutes and lasts about 90 minutes. When applied topically, the solution is absorbed for 7-20 minutes, depending on the dose and place of application. In blood plasma, it binds to proteins by 50-80%, is metabolized in the liver, and excreted after 4-5 hours by the kidneys, mainly in the form of metabolites.

APPLICATION

Method of application and dosage

The drug is used in the form of solutions of 0.25, 0.5 and 1%, for the preparation of which in the syringe to one part of the drug, respectively, select 7, 3 or 1 part of water for injection.

The maximum permissible dose of the active substance per 1 kg of body weight is: for cats – 2 mg, for horses, pigs under 4 weeks, dogs – 4 mg.

Doses of the drug and the concentration of lidocaine hydrochloride solution for different purposes are listed in the table.

Application The drug solution,% Dose, ml / 1 kg of body weight
horses, pigs under 4 weeks of age, dogs cats
Infiltration anesthesia, medical blockade 0.25 0.8-1.6 0.6-0.8
0.5 0.4-0.8 0.3-0.4
Superficial anesthesia of the skin, mucous membranes and synovial membranes, conduction, epidural anesthesia one 0.2-0.4 0.15-0.2
2 0.1-0.2 0.07-0.1
Spinal anesthesia 2 0.1-0.2 0.07-0.1

To prolong the effect of the anesthetic for every 10 ml of lidocaine hydrochloride solution add 0.1 ml of 0.1% adrenaline solution.

*Kilograms to Pounds conversion table

Kilograms (kg) Pounds (lb) Pounds+Ounces
(lb+oz)
0.1 kg 0.220 lb 0 lb 3.527 oz
1 kg 2.205 lb 2 lb 3.274 oz
5 kg 11.023 lb 11 lb 0.370 oz
10 kg 22.046 lb 22 lb 0.740 oz

Reservation

Use with caution in animals with liver disease, congestive heart failure, shock and hypovolemia with severe respiratory depression, hypoxia, during lactation. In the latter case, the drug is used only when the expected benefit to the female outweighs the potential risk to the young.

Do not mix with other drugs in one syringe. Do not combine with barbiturates, curare-like drugs, with drugs that depress or excite the CNS.

When used in therapeutic doses, no side effects are observed, but from the nervous system and senses may be depression or agitation, disorientation, vomiting, sweating, visual disturbances, tremor, convulsions, respiratory depression, apnea. After administration of large doses of the drug may decrease blood pressure, bradycardia, arrhythmia, shock, cardiac arrest, and sometimes allergic reactions.

When a needle enters a vessel and lidocaine enters the blood, collapse may occur. In this case, it is necessary to use vasoconstrictors and cardiac drugs.

In case of overdose, drowsiness, visual disturbances, vomiting, lowering of blood pressure, muscle tremors are possible. In the case of rapid administration, there is hypotension, vascular collapse, convulsions, depression of the respiratory center. Allergic reactions with the onset of anaphylactic shock are possible. With a decrease in heart rate is allowed to enter 0.5-1 mg of atropine sulfate.

Indications

Used for horses, pigs up to 4 weeks of age, dogs, cats for all types of local anesthesia (superficial, infiltrative, conductive, epidural, spinal, intra-articular), therapeutic blockades of peripheral nerves, nerve plexuses in pain and acute inflammation.

Contraindications

Do not administer to animals with hypersensitivity to lidocaine and other amide drugs, during pregnancy, with severe bleeding or infection of possible injection sites, diseases of the cardiovascular system, liver dysfunction accompanied by a decrease in hepatic blood flow.

Storage conditions

In the manufacturer’s packaging, in a dry, dark place at temperatures from +3 to +25 ° C.

After opening the bottle, store the drug in the refrigerator and use it within 10 days.

Shelf life

3 years.

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