AkaroKILL (fipronil, cyfluthrin, pyriproxyfen) Flea & Tick Drops for dogs 20-40 kg, 4ml*3piece
A clear, light yellow solution.
1 ml of the drug contains active ingredients: fipronil – 70 mg, cyfluthrin – 3 mg, pyriproxifen – 20 mg.
Excipients: ethyl acetate, polyethylene glycol-400.
AkaroKILL belongs to the combined insectoacaricidal veterinary drugs.
ATC vet QP53, ectoparasiticides, insecticides and repellents (QP53AX65, fipronil, combinations).
The drug has a pronounced activity against the preimaginal and imaginal phases of development of fleas (Stenocephalides canis, Ctenocephalides felis), lice (Linognatus setotus), lice (Trichodectes canis), sarcoptoids (Sarcoptes canis, Sarcoptes cultes cultis, ticks (Ixodes ricinus, Rhipicephalus sanguineus, Dermacentor reticulatus, Ixodes scapularis, Dermacentor variabilis), as well as a repellent action against dipterans, including blood-sucking flies (Stomoxys calcitransidae), gadflies (Tabulidae Culidae), gadflies (Tabulidae ).
Fipronil belongs to the group of phenylpyrosols, the mechanism of action of which is to block the GABA-dependent receptors of arthropods and disrupt neuromuscular transmission, which leads to their paralysis and death.
Pyriproxyfen is an analogue of natural juvenile hormones, disrupting the processes of chitin synthesis and molting of larvae, prevents the development of full-fledged pupae and causes the death of insects at the preimaginal phases of development, which leads to the termination of the replenishment of the population at the stage of egg and larva, prevents the appearance of sexually mature insects on animals and in their places content.
Cyfluthrin belongs to the group of synthetic pyrethroids, has a contact insectoacaricidal effect, blocking the transmission of nerve impulses and causing paralysis and death of arthropods, as well as a long-term repellent effect against mosquitoes, midges, horseflies and flies.
After applying the drug to the skin of an animal, its active components, practically not absorbed into the systemic circulation, accumulate in the epidermis, hair follicles and sebaceous glands, providing a long-term contact insecticidal and repellent effect. The duration of the protective effect of the drug against fleas, lice and lice is 6-8 weeks, against ixodid ticks and dipterans – 3-4 weeks.
According to the degree of impact on the body, AkaroKILL belongs to moderately hazardous substances (hazard class 3 according to GOST 12.1.007-76), in recommended doses it does not have skin irritating, resorptive toxic and sensitizing effects. Causes minor irritation in eye contact. The drug is toxic to bees, as well as fish and other aquatic organisms.
AkaroKILL is used in dogs from 10 weeks of age for the treatment of entomoses caused by fleas, lice and lice, acarosis caused by sarcoptoid and ixodid ticks, as well as to protect animals from the attack of blood-sucking dipterans.
AkaroKILL is applied to animals by drip on dry intact skin in places inaccessible for licking (the area of the back between the shoulder blades or the area of the neck at the base of the skull), in the doses indicated in the table:
|Type and weight of the animal||Dose of the drug, ml per animal|
|Dogs and puppies from 2 to 10 kg||1 ml|
|Dogs and puppies from 10 to 20 kg||2 ml|
|Dogs and puppies from 20 to 40 kg||4 ml|
|Dogs weighing more than 40 kg||5.5 ml|
Before using on a pipette tube, unscrew the protective cap and, holding it vertically upwards with the nose, cut off the tip of the nose (about 1 mm). Spreading the hair on the body of the animal, apply the drug to the skin in places inaccessible for licking (between the shoulder blades at the withers and along the back), at 2-5 points (depending on the body weight of the animal). To prevent the solution from flowing out to one point, do not press hard on the pipette tube during application!
The duration of the protective action is: against ticks – 1 month; from insects in dogs – 3 months and in cats – 2 months. The repeated procedure should be carried out no more than once a month. In order to prevent re-infestation, the bedding for the animal should be replaced or treated with an approved insecticide-acaricidal agent according to the package insert. Do not apply the drug to damp and / or damaged skin, or bathe and wash the animal within 48 hours after treatment.
The effect of the drug manifests itself in 12-24 hours, taking this into account, treatments should be carried out no later than 24 hours before the intended walking of animals in places where ectoparasites are possible (parks, squares, forests).
To destroy ixodid ticks on the body of the animal, the drug in the amount of 1-2 drops is applied to the tick and the place of its attachment to the skin. If the tick does not spontaneously fall off within 20-30 minutes, it is carefully pulled out of the body and destroyed.
Repeated treatments to prevent the attack of insects and ixodid ticks and the prevention of blood-parasitic diseases (babesiosis, ehrlichiosis, borreliosis) are carried out according to indications during the entire season of parasite activity, but not more often than once a month.
For the treatment of otodectosis (ear scabies), the drug is used once in each ear, 2-3 drops (drops must be injected into both ears). For even distribution of the drug, the auricle is folded in half and lightly massaged at the base. The remainder of the drug from the pipette used (based on the weight of the animal) is applied to the skin between the shoulder blades. In the course of treatment, it is recommended to clean the ear canal from exudate and scabs, and in case of complications from otitis media, prescribe antimicrobial and anti-inflammatory drugs. If necessary, after 10-12 days, the course of treatment is repeated under the control of microscopy of scrapings.
In psoroptosis, sarcoptic mange and notoedrosis, the drug is used 2-3 times with an interval of 10-12 days until the animal’s clinical recovery, which is confirmed by two negative results of microscopic examinations of scrapings from the affected skin areas. In sarcoptoidosis complicated by infection of bacterial or fungal etiology, the use of immunomodulatory, antibacterial or antifungal agents is recommended.
Individual intolerance to the components of the drug (including a history). Pregnant and lactating females, weakened, emaciated, sick with infectious diseases and recovering animals, puppies and kittens under 10 weeks of age cannot be processed. Auricular use of the drug (for ear scabies) is not allowed in case of a bursting of the tympanic membrane. Do not apply the drug to damp, damaged skin.
The animal may experience hypersalivation, muscle tremors, and vomiting. In this case, the drug is washed off with water and detergent and general measures are applied to remove it from the body.
At the first use of the drug, in some cases, the animal has a rapidly passing anxiety or depression, hypersalivation.
Violations of the drug use regimen should be avoided, as this can lead to a decrease in its effectiveness. If the next treatment is missed, it should be carried out as soon as possible in the same dose.
When using the drug in accordance with this instruction, side effects and complications in animals, as a rule, are not observed. In case of increased individual sensitivity of the animal to the components of the drug and the manifestation of allergic reactions, the drug is washed off with water and detergent and, if necessary, desensitizing therapy is carried out.
The drug should not be used in conjunction with other insect-acaricidal veterinary drugs for the treatment of animals.
The drug is not intended for use in productive animals.
When working with the drug, you should follow the general rules of personal hygiene and safety measures provided for when working with veterinary drugs.
Do not smoke, drink or eat while working. After finishing work, wash your hands with warm water and soap.
In case of accidental contact of the drug with the skin or mucous membranes of the eyes, they must be rinsed with plenty of running water. People with hypersensitivity to the components of the drug should avoid direct contact with the drug. In case of allergic reactions or accidental ingestion of the drug into the human body, you should immediately contact a medical institution (you should have instructions for use of the drug or a label with you).
It is forbidden to use empty pipettes from the preparation for household purposes, they must be disposed of with household waste.
4,0 ml polyethylene pipette tubes inserted in cardboard boxes.
In a hermetically sealed package in a dry, dark place and out of reach of children, separately from food and feed, at a temperature from 2 ° C to 25 ° C.
With repeated use of the drug, after the first opening of the pipette tube, it must be tightly closed and stored in an upright position with the cap facing up.
Shelf life is 2 years.
For use in veterinary medicine!