Bravecto spot it drops for cats weighing from 1.2 to 2.8 kg., Against ticks and fleas

BRAVEKTO Spot It for cats is a solution for external use against ticks and fleas based on fluralaner.

YOUR CAT CAN WALK ANYWHERE, FLEAS AND TITLES ALSO.

Key features:

• Prevention of infestation by ticks and fleas for up to 12 weeks.
• Used for otodectosis in cats.
• It can be used for all cats weighing from 1.2 kg and kittens over 11 weeks old.
• Easy to apply with the applicator.
• Reduced number of preventive treatments throughout the year.

1 DOSE = 12 WEEKS OF TICK AND FLEA PREVENTION!

DANGER ON THE STREET

Despite the fact that in the modern world the cat often lives at home, many cats still go for a walk outside or in the warm season they live outside the city, for example, in the country. On the street, a cat can be trapped by uninvited guests – ticks.

A PETS MAY ALSO BE AT RISK

Even if the cat constantly lives at home, fleas can get on it from an already infected animal (dog or cat) that is on the street, living in the entrance, as well as from rodents living in basements. Ticks can get on a domestic cat from human clothing or from dogs.

BRAVEKTO is used in cats as a prophylaxis against infection with ixodid ticks every 12 weeks.

The action of BRAVEKTO against fleas develops within 12 hours, against ticks within 48 hours and lasts for up to 12 weeks.

BRAVEKTO acts on fleas prior to oviposition.

BRAVEKTO can be used as a drug for the treatment of otodectosis in cats.

Fluralaner, a component of BRAVEKTO chewable tablets, is now available as a drop on the withers for cats. Fluralaner blocks two separate biochemical pathways in the membrane of parasite nerve cells: the gamma-aminobutyric acid (GABA) receptor and the glutamate receptor.

PHARMAKINETICS

The fluralaner molecule is absorbed at the site of external application, after which it is distributed throughout the cat’s body. The absorption characteristics provide the maximum plasma concentration in the period from the 3rd to the 21st day after the application of the drug. A low rate of elimination from plasma (T1 / 2 = 12 days) in combination with a high degree of binding to plasma proteins promotes a stable systemic effect. These properties provide fluralaner concentration for up to 12 weeks after topical application. Fluralaner is excreted mainly through the digestive tract.

The BRAVEKTO spot-on drip applicator is equipped with an easy-to-use lid. The pipette is opened by turning the cap.

ATTENTION! The cap remains on the applicator and cannot be removed.

Application scheme:

1 Immediately before use, open the bag and remove the pipette. When opening the pipette, it is necessary to hold the base or the upper rigid part under the cap in an upright position (cap up).

2 Turn the cap clockwise or counterclockwise one full turn.

3 After the inner sealed membrane has ruptured, the pipette is open and ready for use.

4          The cap cannot be removed.

5 For ease and convenience of application, the cat should be standing or lying so that the back is in a horizontal position. Gently squeeze the dropper and apply all of its contents directly to the cat’s skin.

Instructions for use of the drug BRAVEKTO Spot On (solution for spot application).

GENERAL INFORMATION

Bravecto Spot On.

There are the following types of the drug:

• BRAVEKTO Spot It for cats 112.5 mg (solution for spot application for cats weighing 1.2 – 2.8 kg).
• BRAVEKTO Spot It for cats 250 mg (spotting solution for cats weighing 2.8 – 6.25 kg).
• BRAVEKTO Spot It for cats 500 mg (solution for spot application for cats 6.25 – 12.5 kg).

1.0 ml of the preparation contains 280 mg of fluralaner and excipients up to 1 ml.

In appearance, the drug is a clear solution from colorless to yellow.

The drug is stored in a place protected from direct sunlight, at a temperature from + 2 ° C to + 30 ° C. Do not freeze.

PHARMACOLOGICAL PROPERTIES

Fluralaner, which is part of the drug, is an acaricide and an insecticide. It is effective against ixodid ticks (Ixodes ricinus Ixodes scapularis, Ixodes hexagonus, spp., Dermacentor reticulatus spp., Haemaphysalis elliptica and Rhipicephalus sanguineu), Sarcoptes spp., Otodeclox spp.

Fluralaner is a potent inhibitor of certain parts of the arthropod nervous system, acting antagonistically on voltage-independent chlorine ion transport channels (GABA receptor and glutamate receptor).

After topical application, fluralaner is rapidly absorbed into the coat, skin and adjacent tissues, from where it slowly enters the vascular system. The plateau level is reached in plasma 7-63 days after application, after which the concentration decreases slowly. Fluralaner is well distributed in tissues and reaches high concentrations in adipose tissue, liver, muscle and kidney. Long-term storage and slow elimination from plasma and the absence of intensive metabolism provide effective concentrations of fluralaner during the time interval between drug applications. Fluralaner is excreted unchanged in feces and, to a very small extent, in urine.

ORDER OF APPLICATION OF THE PREPARATION

BRAVEKTO Spot It is used in cats for the treatment and prevention of tick and flea infestations, as well as for the treatment of otodectosis caused by Otodectes spp. In cats. It can be used as part of a comprehensive treatment for allergic dermatitis caused by fleas. The preventive effect of flea and tick infestation in cats and dogs lasts for 12 weeks.

The effect after application of the drug develops within 12 hours (from fleas) and 48 hours (from ticks) for cats.

Open one sachet immediately before use and remove the pipette. To open, hold the pipette at the base or by the top below the cap in an upright position (tip up). The twist-off cap is turned in the direction or counterclockwise one full turn. The cap remains on the pipette – it cannot be removed completely. The pipette is open and ready for use when a click is felt from the seal break.

Method of administration and dosage for cats:

BRAVEKTO Spot It is used for cats in accordance with the table given in the instructions (corresponds to one dose of 40-94 mg of fluralaner per 1 kg of body weight).

For cats weighing more than 12.5 kg, use the combination of two pipettes that best matches the body weight.

For cats weighing up to 6.25 kg, the drug should be applied in one place, at the base of the skull; for cats weighing over 6.25 kg – in two places.

During the use of the drug, the cat should stand or lie so that its back is in a horizontal position. Place the pipette tip over the cat’s head.

Gently squeeze the pipette, applying the entire contents of the pipette directly to the cat’s skin.

For optimal control of infestation by fleas and ticks, this product should be used at intervals of 12 weeks.

Do not use in case of known allergy to the active substance or components of the preparation.

There is no data on the use of the drug in cats during pregnancy and lactation.

In some cases, skin reactions may occur at the site of application, in particular, redness or itching.

Lethargy / convulsions / anorexia or nausea / increased salivation may occur in cats shortly after use.

Overdose .

No side effects were noted after application in kittens aged 11-13 weeks (body weight 1.2-1.5 kg) overdose up to 5 times the maximum recommended dose 3 times at shorter intervals than recommended (intervals of 8 weeks ).

Precautions for use in animals:

Do not allow animals to get this drug in the eyes. Do not apply directly to damaged skin. Avoid contact with treated areas (application site) until dry. Cats should not be allowed to swim in bodies of water, immerse them in water, or wash them for 3 days after using the drug.

Due to the lack of information, this drug should not be used:

• kittens less than 11 weeks of age
• cats weighing less than 1.2 kg

PRECAUTIONARY MEASURES

When working with the drug, you should follow the generally accepted rules of personal hygiene and safety measures provided for working with veterinary medicinal products.

In case of contact with the skin or eyes, thoroughly rinse the affected area with clean water. Wash your hands after using the drug.

This medication is flammable. Keep away from heat, open flames or other sources of ignition.