Сestal (pyrantel, praziquantel) Dewormer for Cats 10 tablets
Description:
Tablets are yellowish-gray with a dividing line in the middle.
Structure:
1 tablet of the drug (400 mg) contains active ingredients:
pyrantel embonate – 230 mg,
praziquantel 20 mg
Excipients: lactose, wheat starch, povidone (K-90), talc, magnesium stearate, dry yeast, flavoring agent, purified water.
Pharmacological properties:
ATCvet QP52A, anti-trematode, anti-nematode and prototype veterinary drugs (ATC-vet QP52AA01 – praziquantel, QP52AF02 – pyrantela embonate).
Cestal cat is a broad-spectrum anthelmintic drug, which contains the active ingredients: praziquantel and pyrantela embonate, effective against tape and round helminths.
Praziquantel is a pyrazinisoquinolone derivative that is rapidly absorbed through the outer shell of tapeworms, resulting in damage and contraction. The consequence of a violation of the penetrating properties of membranes is paralysis of parasites. Praziquantel is rapidly absorbed in the alimentary canal. Its highest concentration in blood plasma is observed 1-2 hours after administration, it is rapidly metabolized and excreted up to 80% in the form of metabolites by the kidneys, with 90% in the first 24 hours.
Pyrantel embonate, a tetrahydropyrimidine derivative, acts as a cholinergic antagonist, causing spastic paralysis of round helminths by depolarizing neuromuscular blockade. In the body of cats, pyrantel is poorly absorbed in the alimentary canal and after administration per os at a dose of 10 mg / kg of body weight, its concentration in blood plasma is 0.005-0.13 μg / ml after 1-3 hours. Pyrantel, absorbed into the circulatory system, is partially metabolized in the liver to N-methyl-1,3-propanodiamine. Half of the dose (50%) of pyrantel is excreted unchanged in the feces, about 7% in the urine unchanged or in the form of metabolites.
Application:
Deworming of cats with nematodes and cestodes: Toxocara cati, Toxascaris leonina; Ancylostoma tubaeforme, Uncinaria stenocephala; Taenia taeniaeformis, Taenia pisiformis, Taenia hydatigena, Dipylidium caninum, Echinococcus multilocularis.
Dosage:
Orally at a dose of 1 tablet per 4 kg of body weight (equivalent to praziquantel 5 mg / kg, pyrantel embonate 57.5 mg / kg).
Cats with body weight Dosage
less than 1 kg ¼ tablet
1-2 kg 1/2 tablet
2-4 kg 1 tablet
4-8 kg 2 tablets
Tablets are fed to cats forcibly or with food. You do not need to follow a preliminary starvation diet.
For prophylaxis, the drug should be used every three months at a time.
For treatment, the drug is prescribed once. In case of severe infestation, the treatment must be repeated after 14 days.
Contraindications:
Do not use in animals with hypersensitivity to the components of the drug, weakened and sick animals.
Caveats:
Not installed.
Release form:
Blisters made of aluminum foil and transparent polyethylene film, 2 tablets each, packed in cardboard boxes of 5 blisters.
Storage:
Store in a dry, dark place at temperatures from +15 to + 25 ° C.
Keep out of reach of children and animals, separate from food and feed.
Expiration date : 2 years.