Irmanil, 5 ampoules of 2 ml
Description:
Oily transparent yellow liquid.
Structure:
1 ml of the drug contains the active ingredient:
estradiol benzoate – 0.2 mg.
Excipients: peanut butter.
Pharmacological properties:
Estradiol benzoate is a steroid hormone that regulates the development and activity of the female reproductive system. The effectiveness of the drug is due to the interaction with the receptors of the cells of the central nervous system, endocrine and genital organs. With an increase in the concentration of estradiol in the blood, estrus is stimulated, and its increased concentration makes it impossible to fertilize the egg. Estradiol is hydrolyzed and inactivated by plasma esterases and liver enzymes, after which the metabolites are excreted in the bile. The half-life in dogs is 60 minutes.
Application:
To prevent unwanted pregnancy in bitches after accidental mating.
Dosage:
The drug is administered subcutaneously or intramuscularly once at a dose of 0.5 ml of the drug per 10 kg of body weight (0.1 mg of estradiol benzoate per 10 kg of animal body weight) on days 3 and 5 after unscheduled mating (counting the day of copulation as day zero). If the bitch mated several times or the mating time is unknown, then the drug is administered three times – on days 3, 5 and 7.
Contraindications:
Do not use in cats.
Do not use in animals during pregnancy and lactation, as well as for diseases of the genital organs (pyometritis, metritis, endometritis) caused by hormonal disorders or inflammatory processes; with tumors of the mammary glands.
Caveats:
Before use, to reduce the viscosity of the drug after storage at low temperatures, warm the bottle in your hand.
Release form:
Glass vials of 2, 5 or 20 ml, closed with a rubber stopper for aluminum rolling, enclosed in a cardboard box.
Storage:
A dry, dark place, inaccessible to children, for temperatures from 5 to 25 ° C.
Expiration date: 2 years. After the first selection from the vial, the drug should be used within 30 days, provided that it is stored in a dark place at a temperature of 2 to 8 ° C.
For use in veterinary medicine!