Mipran for cats, 4 Tablets
Original price was: 31.50 €.25.25 €Current price is: 25.25 €.
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Mipran for cats, 0.175 g, 4 Tablets
Description
Tablets are white or light gray, oval in shape with a dividing notch.
Composition
1 tablet (0.175 g) contains active ingredients:
- milbemycin oxime — 8.0 mg,
- praziquantel — 20.0 mg.
Excipients: glucose, lactose monohydrate, calcium carbonate, talc, potato starch, orysil, croscarmellose sodium, calcium stearate.
Pharmacological properties
ATCvet classification code: QP54 – endectocides; QP54AB51 – milbemycin oxime, combinations.
A combined anthelmintic drug with a broad spectrum of activity against cestodes – Dipylidium caninum, Taenia spp., Echinococcus spp., nematodes – Ancylostoma tubaeforme, Toxocara canis, Dirofilaria immitis.
Milbemycin oxime is a macrocyclic lactone obtained by fermentation of Streptomyces hygroscopicus, type Aureolacrimosus. It is active against larvae and adults of nematodes that parasitize the gastrointestinal tract, larvae of the nematode Dirofilaria immitis (microheartworm). The mechanism of action is due to an increase in the permeability of cell membranes for chloride ions (CI), which leads to polarization of the membranes of nerve and muscle cells, paralysis and death of the parasites.
Praziquantel is an acetylated pyrazine isoquinoline derivative. Active against cestodes and trematodes. Increases the permeability of parasite cell membranes to calcium ions (Ca) and causes membrane depolarization, muscle contraction, and destruction of the tegument, which leads to the death of parasites and their excretion from the animal body.
After oral administration, the maximum concentration of milbemycin oxime in the blood plasma is reached after 2 hours. It is excreted from the body mainly unchanged, the half-life is approximately 13±9 hours.
After oral administration with feed, the maximum concentration of praziquantel in the blood plasma is reached after 1 hour. It is excreted from the body mainly as inactive metabolites in the urine, the half-life is about 3 hours.
Application
Prevention and treatment of cats with infestations caused by cestodes Dipylidium caninum, Taenia spp., Echinococcus multilocularis and/or nematodes Ancylostoma tubaeforme, Toxocara cati.
Prevention of heartworm disease (Dirofilaria immitis) with simultaneous use of a drug against cestodes.
Dosage
The drug is used once during morning feeding with a small amount of food or is administered forcibly to the root of the tongue after feeding.
The recommended therapeutic dose is 2.0 mg of milbemycin oxime and 5 mg of praziquantel per 1 kg of body weight.
The doses of the drug depending on the body weight of cats are indicated in the table.
| Animal weight (kg) | Number of tablets |
| 0,5 -1 | 1/4 |
| >1-2 | 1/2 |
| >2-4 | 1,0 |
| >4-8 | 2,0 |
| >8-12 | 3,0 |
There is no need to use a fasting diet or laxatives before deworming.
The drug can be used for the prevention of heartworm disease in parallel with a drug against cestodes. The preventive effect lasts for one month. For long-term prevention of heartworm disease, it is better to use monotherapy.
Contraindication
Increased individual sensitivity to the drug.
Do not use on sick, exhausted and weakened animals.
Do not use the drug on cats weighing less than 0.5 kg.
Do not use in animals with impaired kidney or liver function.
Reservation
Side effect
Allergic reactions are possible in animals with hypersensitivity to the active ingredients of the drug.
When used in recommended doses, side effects usually do not occur.
Use during pregnancy, lactation
The drug can be used in nurseries and for cats during pregnancy and lactation.
Pregnant cats are given the drug in the last third of pregnancy, lactating cats – 2-3 weeks after calving under the supervision of a veterinarian.
Overdose
In case of overdose, some animals may experience tremors, which resolve within a day and do not require special treatment.
Precautions for personnel
Personnel working with the drug must follow the hygiene and safety rules adopted when working with veterinary drugs.
If the product gets on the skin, mucous membranes or in the eyes, rinse them with plenty of running water.
Release form
Blisters of 4 tablets in an individual cardboard box.
Storage
In a dry, dark place, out of reach of children, at a temperature of 5 to 25 °C.
Expiration date
2 years
