Bravecto Spot-On (fluralaner) for cats weighing over 2.8-6.25 kg 1 pipette

COMPOSITION AND FORM OF ISSUE

1.0 ml of the preparation contains 280 mg of fluralaner and excipients up to 1 ml.

In appearance, the drug is a clear solution from colorless to yellow.

Bravecto Spot On is available in pipettes, packed in 0.4 ml laminated aluminum sachets (Bravecto Spot On 112.5 mg, for small breed cats); 0.89 ml (Bravecto Spot On 250 mg, for medium-sized cats); 1.79 ml (Bravecto Spot On 500 mg, for large breed cats), with a high density polyethylene cap. Pipettes are packed in 1 or 2 pieces in cardboard boxes along with instructions for use.

The drug is dispensed without a veterinarian’s prescription.

PHARMACOLOGICAL PROPERTIES

Fluralaner, which is part of the drug, is an acaricide and an insecticide. It is effective against ixodid ticks ( Ixodes spp., Dermacentor spp., Haemaphysalis elliptica  and  Rhipicephalus sanguineus ), as well as  Sarcoptes spp., Otodectes spp . and fleas ( Ctenocephalides spp .).

Fluralaner is a potent inhibitor of certain parts of the arthropod nervous system, acting antagonistically on voltage-independent chlorine ion transport channels (GABA receptor and glutamate receptor).

After topical application, fluralaner is rapidly absorbed into the coat, skin and adjacent tissues, from where it slowly enters the vascular system. The plateau level is reached in plasma 7-63 days after application, after which the concentration decreases slowly. Fluralaner is well distributed in tissues and reaches high concentrations in adipose tissue, liver, muscle and kidney. Long-term storage and slow elimination from plasma and the absence of intensive metabolism provide effective concentrations of fluralaner during the time interval between drug applications. Fluralaner is excreted unchanged in feces and, to a very small extent, in urine.

INDICATIONS

Bravecto Spot It is used in cats for the treatment and prevention of tick and flea infestations, as well as for the treatment of otodectosis caused by Otodectes spp. It can be used as part of a comprehensive treatment for allergic dermatitis caused by fleas.

The preventive effect of infestation with fleas and ticks in cats lasts for 12 weeks.

The effect after application of the drug develops within 12 hours (from fleas) and 48 hours (from ticks).

DOSES AND METHOD OF APPLICATION

Open one sachet immediately before use and remove the pipette. To open, hold the pipette at the base or by the top below the cap in an upright position (tip up). The twist-off cap is turned in the direction or counterclockwise one full turn. The cap remains on the pipette – it cannot be removed completely. The pipette is open and ready for use when a click is felt from the seal break.

Bravecto Spot On for cats is used according to the table below (corresponds to one dose of 40 – 94 mg of fluralaner per 1 kg of body weight).

For cats weighing more than 12.5 kg, use the combination of two pipettes that best matches the body weight.

During the use of the drug, the cat should stand or lie so that its back is in a horizontal position. Place the pipette tip over the cat’s head. Gently squeeze the pipette, applying the entire contents of the pipette directly to the cat’s skin. For cats weighing up to 6.25 kg, the drug should be applied in one place, at the base of the skull; for cats weighing over 6.25 kg – in two places.

For optimal control of infestation by fleas and ticks, this product should be used at intervals of 12 weeks.

SIDE EFFECTS

No side effects were noted after application in kittens aged 11-13 weeks (body weight 1.2 – 1.5 kg) overdose up to 5 times the maximum recommended dose 3 times at shorter intervals than recommended (intervals of 8 weeks ). In cats, in some cases, skin reactions may occur at the site of application, in particular, redness or itching. Lethargy / convulsions / anorexia or nausea / increased salivation may occur shortly after application.

CONTRAINDICATIONS

A contraindication to use is the individual hypersensitivity of the animal to the active substance or components of the drug.

Precautions for use in animals .

· Do not allow animals to get this drug in the eyes.

· Do not apply directly to damaged skin.

· Avoid contact with treated areas (application site) until dry.

· Dogs and cats should not be allowed to swim in bodies of water, immerse them in water or wash them for 3 days after using the drug.

· Due to the lack of information, this drug should not be used: kittens less than 11 weeks of age and / or cats weighing less than 1.2 kg.

SPECIAL INSTRUCTIONS

The drug can be used in dogs during pregnancy and lactation. There is no data on the use of the drug in cats during pregnancy and lactation.

PERSONAL PREVENTION MEASURES

When working with the drug, you should follow the generally accepted rules of personal hygiene and safety measures provided for working with veterinary medicinal products.

In case of contact with the skin or eyes, it is necessary to thoroughly rinse the affected area with clean water. Wash your hands after using the drug.

This medication is flammable. Keep away from heat, open flames or other sources of ignition.

STORAGE CONDITIONS

Store in closed manufacturer’s packaging separately from food and feed in a place protected from direct sunlight at a temperature of 2 ° C to 30 ° C. Do not freeze.

The medicinal product should be stored out of the reach of children.

The shelf life of the drug, subject to storage and transportation conditions, is 2 years from the date of manufacture.

The medicinal product must not be used after the expiration date.

Unused medicinal product is disposed of in accordance with legal requirements.