Equisedan solution (detomidine) 10 ml
Original price was: 162.30 €.122.80 €Current price is: 122.80 €.
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Equisedan solution (detomidine) Domosedan analog, 10 ml
Description:
Transparent colorless liquid.
Composition:
1 ml of the drug contains the active substance:
detomidine hydrochloride – 10 mg;
Excipients: sodium chloride, methylparahydroxybenzoate, water for injections.
Pharmacological properties:
Detomidine hydrochloride is an agonist of α2-adrenergic receptors. Equisedan causes suppression of the central nervous system and an increase in the pain threshold. The effect of detomidine is dose-dependent:
small doses produce mild sedation without analgesia, while large doses cause significant sedation and analgesia. When administered intravenously, the drug acts faster, when administered intramuscularly – more slowly.
The drug is quickly absorbed after intramuscular administration.
The maximum concentration in blood plasma is reached after 15-30 minutes. Detomidine is quickly distributed in the body, binding to blood plasma proteins is 85-90%, is oxidized in the liver, and is partially metabolized in the kidneys.
Most of the drug’s metabolites are excreted in the urine. The half-life is 1-2 hours.
Application:
The drug is used to obtain a sedative effect and analgesia of horses during surgical operations and various clinical studies, when immobilizing animals for their capture and transportation, as well as to prevent aggressiveness and timidity of animals.
Dosage:
Equisedan is administered to horses intramuscularly or intravenously. The degree of sedative effect can be adjusted by selecting the dose of the drug.
The drug is administered intravenously slowly (1 ml per minute) in the following doses:
| A sedative effect is required | Dose | Onset of effect (min *) | Duration, actions (min *) | ||
| µg/kg | ml/100 kg | in/in | in/m | ||
| Light | 10 – 20 | 0.1 — 0.2 | 3 | 5 | 30-60 |
| Average | 20 – 40 | 0.2 — 0.4 | 2 | 5 | 30-60 |
| Deep | 40 – 80 | 0.4 — 0.8 | 1 | 5 | 30-120 |
* – The time is approximate and may vary in individual animals.
It is recommended to use 2 sterile needles: one for filling the syringe from the vial, the other directly for injection.
As soon as the necessary dose of the drug is drawn into the syringe, it should be disconnected from the needle located in the vial.
An injection needle is inserted into the animal, and only then the syringe with the drug is attached to it.
*Kilograms to a Pounds conversion table
| Kilograms (kg) | Pounds (lb) | Pounds+Ounces (lb+oz) |
| 0.1 kg | 0.220 lb | 0 lb 3.527 oz |
| 1 kg | 2.205 lb | 2 lb 3.274 oz |
| 5 kg | 11.023 lb | 11 lb 0.370 oz |
| 10 kg | 22.046 lb | 22 lb 0.740 oz |
Side effects:
The introduction of Equisedan can cause arrhythmia, which is temporary in nature, impaired coordination, increased sweating.
Sometimes there is a slight tremor of individual muscles or muscle groups.
Contraindications:
It is not recommended to use Equisedan together with sympathomimetics.
The drug is not used for horses in the last third of foaling (pregnancy).
Increased individual sensitivity to the drug.
Caution:
Slaughter of horses for meat is allowed 7 days after stopping the administration of the drug.
The meat of animals forcibly slaughtered before the end of the specified period can be used for feeding fur animals or for the production of meat and bone meal.
Precautions:
When working with the drug, you should follow the general rules of personal hygiene and safety techniques, provided for when working with medicinal products for animals.
It is prohibited to use empty vials from the medicinal product for domestic purposes.
Release form:
Bottles made of glass, closed with a rubber stopper under an aluminum break-in of 5 and 10 ml.
Storage:
In a dry place protected from direct sunlight, inaccessible to children, at a temperature of 15° to 25°C.
Shelf life:
2 years from the date of manufacture; after opening the bottle – up to 28 days.
It is forbidden to use the drug after the expiry date.
For use in veterinary medicine!
