Pillkan 20 (Pillkan 20) 8 sugar cubes. A drug for delaying and interrupting estrus in bitches and reducing the sexual activity of males.
A drug for delaying and interrupting estrus in bitches and cats, reducing the sexual activity of males.
Composition and release form: Pillcan 20 contains 20 mg of the active ingredient megestrol acetate and fillers. Pillcan is a white sugar cube with a dividing groove in the middle, soluble in water, weight 5.5 g. Pillcan is produced in sealed plastic blisters of 8 cubes each.
Pharmacological action: Pillcan’s active ingredient, megestrol acetate, has progesterone-like properties. It inhibits the secretion of gonadotropins (luteonizing hormone and follicle-stimulating hormone) by direct action on the hypothalamus. If the drug is given before the onset of estrus, it, in appropriate doses, inhibits the secretion of gonadotropic hormones and prevents ovulation. If the drug is given at the beginning of the follicular phase (the second or third day of estrus), it leads to the interruption of estrus. When administered to males, megestrol acetate has an indirect effect on the regulation of behavioral traits. Megestrol acetate is easily absorbed in the intestines, in the liver it is biotransformed and excreted mainly through the urine in 1-2 days in the form of salts.
Doses and method of administration: The drug Pillcan is used to delay and interrupt estrus in bitches and to reduce the sexual activity of males. The sugar cube is fed from the owner’s hand or added to food or water. Interruption and delay of heat in bitches… Start giving the drug Daily dosage Duration of the course of giving the drug Delay in estrus 7-15 days before the start of estrus 1 cube Pillcan 20 per 40 kg of animal weight. The maximum course of giving the drug is 32 days. Termination of estrus no later than on the third day after signs of estrus appear 1 Pillcan 20 cube per 10 kg of animal weight. During the first 3 days of the course, give a daily dose, then over the next seven days – half of the daily dose. The drug is given to bitches for as long as it is desirable to delay estrus. The flow will begin a few days after you stop giving the drug. When signs of satyriasis (sexual arousal) appear in males, they are given 1 cube of Pillcan 20 per 10 kg of live weight per day, for 8 days, then give ½ cube of Pillcan 20 per 10 kg of live weight of the animal for 8 days.
Side effects: With prolonged or repeated use of the drug, the following side effects are possible: change in character, development of the mammary gland, increased appetite.
Contraindications Do not use Pillcan to interrupt estrus if 4 days have passed since the beginning of estrus in bitches. It is forbidden to use the drug if the following contraindications are found in an animal: pregnancy, diseases of the reproductive system (pyometra, metritis, endometritis,
etc.), breast tumors, diabetes. Do not use before puberty in animals.
Special instructions: It is recommended to use only two courses of giving the drug per year.
Storage conditions: Store the drug in the manufacturer’s packaging with caution (list B) in a dry place at a temperature of 15 to 20 C. The warranty period is 4 years from the date of manufacture.