Provevet, 10 tablets
Description:
Tablets from white to grayish color with a specific odor.
Structure:
One tablet (0.12 g) of the drug contains the active ingredient:
medroxyprogesterone acetate – 5 mg.
Excipients: potato starch, lactose, talc, calcium stearate.
Pharmacological properties:
ATCvet QG, veterinary drugs affecting the genitourinary system and sex hormones (QG03A hormonal contraceptives for systemic use).
The active ingredient of the drug is medroxyprogesterone acetate – a synthetic progestin, an analogue of progestins produced by the corpus luteum. The action consists in converting the proliferative endometrium into a secretory endometrium, enhances myometrial hypertrophy and suppresses uterine contraction. Depending on the dose, it suppresses the secretion of pituitary gonadotropins, has an anti-insulin effect. In animals, medroxyprogesterone acetate has a pronounced adrenocortical effect and suppresses the release of adrenocorticotropic hormone and cortisol.
Medroxyprogesterone has an antiestrogenic effect and reduces plasma testosterone levels in males.
Application:
The drug provervet is used for females and males of dogs and cats:
bitches and cats to delay and interrupt estrus;
for cats and males – to reduce sexual activity and correct undesirable behavior (marking the territory with urine, intraspecific aggression, increased excitability).
The drug also prevents the onset of signs of pseudo pregnancy and lactation.
Dosage:
The drug provervet is administered orally, forcibly to the root of the tongue or with a small amount of food 1-2 hours before the main feeding of the animal.
Cats:
to prevent estrus – 1 tablet once a week, use the drug during the period when it is desirable to delay estrus. After discontinuation of the drug, hunting begins in about 2 weeks. The drug should not be used for more than 18 months;
to stop estrus – 1 tablet once a day for 3-5 days until the signs of estrus cease, no later than on the third day after the onset of estrus, and then 1 tablet once a week. It is impossible to interrupt estrus more often than 2 times a year.
Cats:
when signs of sexual arousal appear, to calm and correct undesirable behavior (labeling the territory with urine, intraspecific aggression, increased excitability) – 1 tablet once a day for 8 days and then 1 tablet – once a week.
Bitches:
to prevent estrus – 1 tablet per 10 kg of body weight of the animal once a day 7-15 days before the cessation of estrus, after stopping the use of the drug, hunting begins in a few days; the drug should not be used continuously for more than 32 days;
to stop estrus – 1 tablet per 10 kg of the animal’s body weight once a day for the first 3 days, and then 2 tablets per 10 kg of the animal’s body weight once a day for 7 days until the signs of estrus cease, no later than on the third the day after the onset of estrus. After discontinuation of the drug, estrus usually begins after 4-9 months. It is not recommended to use the drug more often than 2 courses per year.
Males:
when signs of sexual arousal appear, to calm down and correct undesirable behavior (labeling the territory with urine, intraspecific aggression, increased excitability) – 4 tablets per 10 kg of animal body weight per day for 8 days, and then 2 tablets per 10 kg of animal body weight per day for 8 days.
Contraindications:
The drug is not used in animals during pregnancy and lactation and during pseudo pregnancy and lactation!
The drug is not used for diseases of the genitourinary and endocrine systems, violation of the regularity of the sexual cycle, breast tumors, in immature animals (before the first estrus)!
The drug is not used if more than 2 days have passed since the onset of estrus!
Caveats:
With prolonged use, changes in the sexual cycle, enlargement of the mammary glands, excessive appetite and weight gain are possible.
The drug should be used under the supervision of a veterinarian, especially for greyhound dogs.
Release form:
Blisters of 10 tablets. Secondary packaging – cardboard boxes of 10, 20, 50 and 100 tablets.
Storage:
Dry, dark, inaccessible to children, place at a temperature of 10 to 25 ° C.
Expiration date : 3 years.