Description

Clear solution from light yellow to dark yellow.

Composition

1 ml contains active ingredients:

tylosin tartrate-200 mg.

Excipients: benzyl alcohol, propylene glycol, water for injection.

Pharmacological characteristics

Tylosin is a mixture of macrolide antibiotics produced by the Streptomyces fradiae strain, which mainly includes Tylosin A. Tylosin is effective against gram-positive and some gram-negative microorganisms: Streptococcus spp., Staphylococcus spp., Corynebacterium spp., Clostridium spp. Erysipelothrix spp. Pasteurella spp., Vibrio spp. Leptospira spp. Brucella spp. Neisseria spp., Haemophilus spp., Moraxella spp., as well as against mycoplasmas (Mycoplasma spp.), chlamydia (Chlamydia spp.), Rickettsia (Rickettsia spp.), spirochetes (Spirochaetes). Tylosin exhibits a bacteriostatic effect by inhibiting protein synthesis (via an irreversible connection to the 50S subunits of bacterial ribosomes) and microbial cell growth and reproduction, respectively.

Application

Cattle, sheep, goats, treatment of animals suffering from bronchopneumonia, pneumoenteritis, metritis, arthritis, necrotic pododermatitis, contagious agalactia, mastitis, diphtheria of calves, pleuropneumonia of goats, interstitial pneumonia of calves, chlamydial abortions of sheep caused by microorganisms sensitive to tylosin.

Pigs: treatment of animals suffering from enzootic pneumonia, enteritis, dysentery, atrophic rhinitis, erysipelas, staphylococcal arthritis, leptospirosis, MMA syndrome caused by microorganisms sensitive to tylosin.

Dogs, cats: treatment of animals with diseases of the digestive and respiratory tract and animals suffering from otitis, cystitis, metritis, dermatitis, leptospirosis caused by microorganisms sensitive to tylosin.

The drug is also used to treat surgical infections and secondary bacterial infections in viral diseases.

Dosage

Intramuscularly once a day in doses:

cattle-0.25-0.5 ml per 10 kg of body weight;

sheep, goats-0.25-0.5 ml per 10 kg of body weight;

pigs-0.5 ml per 10 kg of body weight;

dogs and cats – 0.25-0.5 ml per 10 kg of body weight.

The drug is discontinued 24 hours after the symptoms disappear, but not later than 5 days after use.

Do not inject more than 20 ml into one part of the body of adult cattle; calves, sheep, goats-15 ml; piglets, pigs-more than 10 ml; dogs, cats-more than 5 ml. If you need a dose greater than the permissible one, it is divided and administered in several places.

Contraindications

Do not use in animals with hypersensitivity to tylosin.

Do not apply to animals in the first week of life.

Do not use in conjunction with penicillins, cephalosporins and lincomycin due to a marked decrease in the antibacterial effect of tylosin.

Do not use for horses, rabbits, Guinea pigs, hamsters.

Precautionary measures

Slaughter of animals for meat is allowed 8 days after the last use of the drug. Human consumption of milk is allowed 4 days after the last use of the drug. Meat and milk received by the specified date are fed to unproductive animals or disposed of, according to the conclusion of a veterinary medicine doctor.

Storage:

Dry, dark, out of reach of children at temperatures from 5°C to 25°C

Shelf life-2 years.

After the first selection from the bottle, the drug is used for 28 days if stored in a dark place at a temperature of 5 ° C to 25 ° C.