Antilact (cabergoline) 7ml
COMPOUND
1 ml of the drug contains an active substance:
cabergoline – 50 mcg.
Excipients: propylene glycol, dicaprilat / dicaprate.
PHARMACEUTICAL FORM
Colorless transparent solution.
PHARMACOLOGICAL PROPERTIES
ATC-VET CLASSIFICATION CODE: QG02CB – PROLACTIN INHIBITORS.
Cabergoline, which is part of the drug, an ergoline derivative, acts as an agonist of dopamine receptors, which leads to inhibition of the secretion of prolactin by the pituitary gland, the main hormone of lactogenesis. A decrease in prolactin levels prevents lactation and contributes to the disappearance of clinical signs of false pregnancy in bitches and cats.
After oral administration, the peak of suppression of prolactin secretion is reached after 4-8 hours and lasts for several days, depending on the dose.
Cabergoline is excreted from the body in the form of metabolites, mainly with feces (60%) and, to a lesser extent, with urine (22%).
APPLICATION
ANTILACT is used in bitches and cats to terminate lactation according to clinical indications (for example, during the period of early weaning of puppies and kittens) and to terminate false pregnancies.
DOSAGE
The drug is administered orally with food or directly to the root of the tongue at a dose of 0.1 ml (3 drops, equivalent to 5 μg cabergoline per kg bw) per 1 kg of animal body weight once a day for 4-6 days.
CONTRAINDICATIONS
Do not use in case of individual sensitivity of the animal to cabergoline.
Do not use in pregnant bitches and cats.
Do not use in lactating females during the rearing period.
Do not administer to animals with renal or hepatic impairment.
Do not administer to animals in a state of hypotension.
SIDE EFFECTS
Well tolerated in recommended doses. In the first two days of taking the drug, side effects are rarely possible in the form of vomiting, anorexia, lethargy, which stop on their own and do not require discontinuation of the drug. In case of indomitable vomiting, the drug is canceled.
Very rarely, in animals sensitive to ergoline derivatives, allergic reactions are possible in the form of itching, edema, dermatitis and urticaria, which stop after discontinuation of the drug and the use of antihistamines.
WARNING
Do not use with dopamine antagonists (for example, metoclopramide), as well as with drugs that have antihypertensive effects.
If one or more doses of the drug are missed, treatment should be resumed as soon as possible at the planned dosage and according to the regimen.
SHELF LIFE
2 years.
After opening the bottle – 28 days, provided it is stored in a dark place at a temperature of 5 to 25 ° C.
SPECIAL STORAGE MEASURES
A dark place out of the reach of children at a temperature of 5 to 25 ° C.
RELEASE FORM
7 ml dark glass dropper bottles.
FOR USE IN VETERINARY MEDICINE!