Description

Round tablets from white to yellow in color, in a shell, with a specific smell of the constituent components.

Composition

1 gram of the drug contains the active substance:

• ronidazole — 250 mg.

The drug is produced in the following forms:

• A tablet weighing 480 mg, containing the active substance ronidazole — 120 mg.
• A tablet weighing 120 mg, containing the active substance ronidazole — 30 mg.

Excipients: sugar, polyvinylpyrrolidone, potato starch, calcium stearate, talc, albumin, powdered milk, flavoring, lactose.

Pharmacological properties

ATCvet QP51, antiprotozoal veterinary drugs.

Ronidazole (a group of nitroimidazole compounds) acts on protozoa, trichomonas and anaerobic bacteria. The connection of the reaction products of ronidazole with the DNA of the simplest cells or bacteria leads to its death. The formation of strong compounds significantly increases the acidic intracellular pH level, which, among other things, confirms the selective action of 5-nitromidazole derivatives against anaerobic bacteria and some protozoa. In addition, as a result of the reaction of ronidazole, products are created, which are intracellular donors of free aerobic radicals, which additionally damage intracellular molecules other than DNA. This increases cellular destruction and leads to the fastest death of protozoa or bacteria.

After oral administration, ronidazole is almost completely quickly absorbed from the digestive tract and reaches the maximum concentration in the blood plasma after 12-14 hours. Its bioavailability is more than 90%. The plasma half-life of ronidazole after oral administration in most animals is approximately 11 hours, blocking its reproduction by inhibiting DNA synthesis.

The drug in the recommended doses has no sensitizing, embryotoxic and teratogenic effects.

Application

Prevention and treatment of dogs and cats with diseases of the gastrointestinal tract and other organs and tissues caused by the simplest Trichomonas spp. and Giardia spp.

Dosage

Dogs: in the treatment of animals affected by Giardia spp. tablets are used orally, once a day in the following doses: 30-50 mg of ronidazole per 1 kg of the animal’s body weight, or:

• 1 tablet (weighing 480 mg) per 2.4 3-4 kg of animal body weight;
• 1 tablet (weighing 120 mg) per 0.6-1 kg of animal body weight.

The course of treatment is 7 days.

Cats: in the treatment of animals affected by giardiasis (giardiasis), tablets are used orally, once a day, in the following doses: 30 mg of ronidazole per 1 kg of body weight, or:

• 1 tablet (weighing 480 mg) per 4 kg of animal body weight;
• 1 tablet (weighing 120 mg) per 1 kg of animal body weight.

The course of application — within 7 days.

In the treatment of infections caused by Trichomonas fetus, the drug is used orally once a day, in the following doses: 30 mg of ronidazole per 1 kg of body weight, or:

• 1 tablet (weighing 480 mg) per 4 kg of animal body weight;
• 1 tablet (weighing 120 mg) per 1 kg of animal body weight.

The course of application — within 14 days.

Changes in the duration of the course of drug use are determined by the veterinarian, depending on the condition of the animal, the severity and course of the disease, and the results of laboratory tests.

*Kilograms to Pounds conversion table

Contraindication

Increased sensitivity to the components of the drug.

Do not use in pregnant or lactating animals.

Do not use in exhausted animals, animals with signs of viral infection, disorders of the functions of the nervous system, kidneys and liver.

Reservation

Treatment of animals should be combined with disinfection of premises, enclosures, cages where sick animals are kept, to avoid the possibility of re-infection.

Pets should be bathed with shampoo in order to wash off the parasite spores that get on the fur.

When using the drug according to the leaflet, side effects and complications are usually not noted.

In case of an overdose of the drug or increased individual sensitivity of animals to ronidazole during treatment, vomiting or neurological disorders are possible – convulsions, impaired coordination of movements, etc. If such symptoms appear, you should immediately consult a veterinarian for a possible dose adjustment and recommendations for further treatment, and have a leaflet with the drug with you.

Release form

Polymeric containers of 15, 20, 30, 50 tablets. Secondary packaging is a cardboard box with a leaflet.

Storage

Dry, dark, inaccessible to children and animals, place at temperatures from 5 to 25 °C.

Expiration date

3 years.

For use in veterinary medicine!