Threeguard for poultry (tilmicosin, enrofloxacin, trimethoprim) Oral solution, 1000 ml

Description

Transparent yellow solution.

Structure

1 ml of the drug contains active ingredients:

tilmicosin – 50 mg;

enrofloxacin – 50 mg;

trimethoprim – 25 mg.

Pharmacological properties

Tilmicosin is a broad-spectrum antibiotic from the macrolide group. It is effective against the respiratory pathogens M. gallisepticum, M. synoviae, P. multocida, and Ornithobacterium rhinotracheale. Tilmicosin inhibits protein synthesis in microorganisms by interacting with the ribosomes of bacterial cells.

Enrofloxacin is a broad-spectrum antibiotic from the group of fluoroquinolones. The drug has an antimicrobial effect against gram-positive and gram-negative microorganisms (Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp., Pseudomonas, E. coli, Haemophilus spp., Salmonella spp. ., Pasteurella spp. And others), and also acts on mycoplasmas and chlamydia. The mechanism of action is associated with the inhibition of bacterial DNA gyrase, which leads to a violation of bacterial DNA replication.

Trimethoprim is a broad-spectrum antimicrobial agent from the diaminopyrimidine group. The drug has an antimicrobial effect against gram-positive and gram-negative microorganisms (Escherichia coli, Klebsiella spp., Salmonella spp .; Pasteurella spp .; Enterobacter spp., Proteus spp .; Shigella spp .; Staphylococcus spp .; Streptococcus spp .; Haemophilophilus spp .; Chlamydia), and also acts on Toxoplasma and Coccidia. The mechanism of action is associated with the suppression of bacterial dihydrofolic acid reductase.

Application

The drug is used to treat infectious diseases of chickens caused by bacterial microflora sensitive to enrofloxacin, tilmicosin, and trimethoprim: mycoplasmosis, coli infections, salmonellosis, necrotic enteritis, streptococcosis, etc.

Dosage

Chickens: oral administration with drinking water at a dose of 2 ml per 1 liter of drinking water during the first 3 days of life. It is recommended to repeat the treatment of chickens on the 20-22 day of life by drinking the drug for 3 days at a dose of 2 ml per 1 liter of drinking water.

Contraindications

It is not used for animals sensitive to the drug, as well as for laying hens, eggs from which are intended for human nutrition.

Warning

In the case of preparation of the mother liquor, it is necessary to add the preparation to the water. Water with the preparation should be the only source of drinking water during the treatment period!

Slaughter of animals and poultry for meat is allowed 12 days after the last use of the drug. The meat obtained before the specified period is disposed of or fed to unproductive animals, depending on the conclusion of a veterinary doctor.

Release form

10 ml glass bottles or 1-liter plastic cans.

Storage

A dry, dark place out of the reach of children at a temperature of 5 ° C to 25 ° C

Expiration date  – 2 years from the date of manufacture.

After dissolving the drug in water, this solution must be used within 24 hours.