Apramycin 500 mg/g powder 100 g
Original price was: 55.00 €.46.31 €Current price is: 46.31 €.
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Apramycin water-soluble powder for poultry, cattle, pigs, rabbits, sheep, 10o g
Pharmaceutical form: Powder for oral solution
Composition
The powder is loose, fine, from light yellow to light brown, soluble in water.
Apramycin sulfate 500 mg. Excipients: colloidal anhydrous silica, lactose.
Packed in 100 g in polypropylene jars, closed with a plastic lid with a tear-off ring.
Each jar is marked with the name of the manufacturer, its address and trademark, name of the drug, name and content of active substance, mass of powder in the jar, purpose and method of use, storage conditions, storage dates, date of manufacture, batch number and expiration date, inscriptions ” For animals “and provide instructions for use.
Pharmacological properties
Veterinary antibiotic from the group of aminoglycosides. The drug has a bactericidal effect mainly against gram-negative and some gram-positive bacteria , including Escherichia coli, Salmonella spp., Pseudomonas spp., Staphylococcus spp., Streptococcus spp., Streptococcus spp., Proteus spp., Bordetella bronchiseptica, Klebsiella spp., Shigella spp., Campylobacter spp., Campylobacter spp., Brachyspira hyodyy
Not active against anaerobic microorganisms.
The mechanism of antibacterial action of apramycin is due to inhibition of protein synthesis of microorganisms by irreversible binding to the 30S subunit of ribosomes.
When administered orally, Apramycin water-soluble powder is poorly absorbed and reaches a high antibacterial concentration in the gastrointestinal tract. Apramycin is not biotransformed in animals and after oral administration is excreted unchanged in active form, mainly in the feces and partly in the urine.
In the recommended doses does not show embryotoxic, teratogenic, local irritant and allergic effects.
Apramycin water-soluble powder according to the degree of impact on the body is a low-risk substance (hazard class 4 according to GOST 12.1.001-76).
Indications for use
Treatment of gastrointestinal diseases caused by susceptible microorganisms in farm animals (including calves, piglets, lambs and chickens):
- gastroenterocolitis of pigs, sheep and poultry of salmonellosis, colibacillosis, pseudomonas and coccal etiology;
- colibacillosis of broiler chickens and laying hens;
- toxic dyspepsia of calves.
Method of application and dosage
Apramycin water-soluble powder is administered to animals orally with drinking water, and to calves and lambs – with milk or whole milk replacer (WHC) once a day for 5-7 days in the following doses:
| Animal species | Dose of Apramycin water-soluble powder |
| piglets | 15-25 mg / kg body weight |
| The calves | 40-80 mg / kg body weight |
| The lambs | 20 mg / kg body weight |
| Repair young laying hens, broiler chickens | 50-100 mg / kg live weight or 0.5-1 g / l water |
Before use, a single dose of Apramycin water-soluble powder should be dissolved in 5-10 times the volume of liquid (water, milk or ZCM), adding it to the powder, then allow the solution to stand for several minutes, mix again and bring the volume to the desired final concentration.
When using Apramipin water-soluble powder with drinking water (for broiler chickens, laying hens), the calculated dose of antibiotic is recommended to mix with half the daily volume of water consumed. Since iron ions reduce the activity of the antibiotic, the drug solution can not be prepared in rusty metal containers.
The ready aqueous solution of Apramycin water-soluble powder should be used within 3 days, and the solution in milk or ZCM within 24 hours after cooking.
*Kilograms to a Pounds conversion table
| Kilograms (kg) | Pounds (lb) | Pounds+Ounces (lb+oz) |
| 0.1 kg | 0.220 lb | 0 lb 3.527 oz |
| 1 kg | 2.205 lb | 2 lb 3.274 oz |
| 5 kg | 11.023 lb | 11 lb 0.370 oz |
| 10 kg | 22.046 lb | 22 lb 0.740 oz |
Side effect
No data on side effects of the drug are provided.
Contraindication
- Hypersensitivity to apramycin and other aminoglycosides;
- co-administration with β-lactam antibiotics due to decreased antibacterial activity and other aminoglycosides (streptomycin, neomycin, kanamycin, gentamicin) due to possible enhancement of nephrotoxic effects.
Features of application
Special instructions and measures of personal prevention
Slaughter of calf meat treated with Apramycin water-soluble powder is allowed not earlier than 28 days after discontinuation of the drug, and in case of kidney and liver disposal – not earlier than 7 days.
Slaughter of meat of piglets treated with Apramycin water-soluble powder is allowed not earlier than 14 days after discontinuation of the drug; in the case of kidney and liver disposal, meat is allowed to be eaten without restrictions.
Slaughter of lamb meat treated with Apramycin water-soluble powder is allowed not earlier than 30 days after discontinuation of the drug; in the case of kidney and liver disposal, meat is allowed to be eaten without restrictions.
Slaughter of broiler chickens and laying hens for laying hens treated with Apramycin water-soluble powder is allowed no earlier than 6 days after discontinuation of the drug.
Meat of animals forcibly killed before the expiration of this period is used for animal feed or for meat and bone meal.
Personal prevention measures
When working with the medicinal product, the general rules of personal hygiene and safety precautions provided for when working with medicinal products for animals should be observed.
Packaging material is collected and handed over for incineration or processing in accordance with current legislation.
Storage conditions
List B. The drug should be stored in the factory packaging, in a dry, dark place at a temperature of 5 ° to 25 ° C. Shelf life – 2 years.
The drug should be stored out of reach of children.
Package
Bank 100 g
Producer
Huvepharma, Bulgaria
